Dimensions Of Dental Hygiene (11/28, Pratt Machado) reported that new research from the University of North Carolina at Chapel Hill has discovered that men produce higher levels of the inflammatory protein IL-1β, explaining their greater risk for severe periodontitis. This biological mechanism, confirmed in both human and mouse studies, suggests that men are predisposed to rapid periodontal tissue breakdown. The findings propose future sex-specific periodontal therapies targeting the inflammasome pathway, particularly beneficial for men. The study also indicates the necessity to explore different inflammatory pathways in women for tailored treatments.
Link: https://dimensionsofdentalhygiene.com/why-men-face-a-higher-risk-of-periodontal-diseases/